Gearing up chromatin

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چکیده

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Gearing up chromatin

D transcription, RNA polymerase may encounter DNA lesions, which causes stalling of transcription. To overcome the RNA polymerase blocking lesions, the transcribed strand is repaired by a dedicated repair mechanism, called transcription coupled nucleotide excision repair (TC-NER). After repair is completed, it is essential that transcription restarts. So far, the regulation and exact molecular ...

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ژورنال

عنوان ژورنال: Nucleus

سال: 2014

ISSN: 1949-1034,1949-1042

DOI: 10.4161/nucl.29085